Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2131377 | 0.89 | S1PR1 (1.00) | S1PR1S1PR3 | |
| SCHEMBL2123257 | 0.88 | S1PR1 (0.88) | S1PR1S1PR3 | |
| Trifluoroacetic Acid SCHEMBL2122754 | 0.82 | S1PR1 (0.85) | S1PR1 | |
| Trifluoroacetic Acid SCHEMBL2122704 | 0.82 | S1PR1 (0.85) | S1PR1 | |
| SCHEMBL2124411 | 0.81 | S1PR1 (0.83) | S1PR1S1PR3 | |
| SCHEMBL13012458 | 0.79 | S1PR1 (0.80) | S1PR1 | |
| SCHEMBL2129357 | 0.78 | S1PR1 (0.61) | S1PR1S1PR3 | |
| SCHEMBL2124027 | 0.78 | S1PR1 (0.68) | S1PR1 | |
| SCHEMBL2132791 | 0.77 | S1PR1 (0.67) | S1PR1 | |
| Lithium SCHEMBL2132815 | 0.77 | S1PR1 (0.67) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443116-A1 | THIADIAZOLE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF DISORDERS MEDIATED BY SLPL RECEPTORS | Glaxo Group Limited (GB) | 2012-04-25 | — | — | EP | disclosed |
| WO-2010146104-A1 | THIADIAZOLE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF DISORDERS MEDIATED BY SLPL RECEPTORS | GLAXO GROUP LIMITED (GB) | 2010-12-23 | — | — | WO | disclosed |