SCHEMBL21242717

SCHEMBL21242717

CC(=O)[C@H](CCCCNC(=O)CC[C@H](NC(=O)CCC(NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(=O)O)C(=O)O)C(=O)O)NC(C)C

nearest known ligand 0.67

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.67
▸ CCKAR P32238 8/20 0.43
▸ CCKBR P32239 8/20 0.43
▸ FOLH1 Q04609 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26059901 0.99 GLP1R (0.68) GLP1RCCKARCCKBRFOLH1
SCHEMBL26059786 0.94 GLP1R (0.65) GLP1RCCKARCCKBRFOLH1
SCHEMBL25912500 0.94 GLP1R (0.72) GLP1RCCKARCCKBRFOLH1
SCHEMBL25912496 0.94 GLP1R (0.72) GLP1RCCKARCCKBRFOLH1
SCHEMBL24494709 0.93 GLP1R (0.67) GLP1RCCKARCCKBRFOLH1
SCHEMBL21242874 0.91 GLP1R (0.69) GLP1RCCKARCCKBRFOLH1
SCHEMBL21242938 0.91 GLP1R (0.69) GLP1RCCKARCCKBRFOLH1
SCHEMBL21242700 0.91 GLP1R (0.69) GLP1RCCKARCCKBRFOLH1
SCHEMBL21242892 0.91 GLP1R (0.69) GLP1RCCKARCCKBRFOLH1
SCHEMBL19786713 0.91 GLP1R (0.69) GLP1RCCKARCCKBRFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2758426-B1 NOVEL GLUCAGON ANALOGUES NOVO NORDISK AS (DK) 2019-08-07 — — EP disclosed
Send feedback