SCHEMBL21242746

SCHEMBL21242746

CCCCCNC(=O)CC[C@H](NC(=O)CC[C@H](NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CCC(NC(=O)CCCCCCCCCCCCCCC(=O)O)C(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.81

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 8/20 0.81
NOD1 Q9Y239 7/20 0.55
CCKAR P32238 2/20 0.48
CCKBR P32239 2/20 0.48
EPHX2 P34913 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14822000 1.00 GLP1R (0.81) GLP1RNOD1CCKARCCKBREPHX2
SCHEMBL15360147 1.00 GLP1R (0.81) GLP1RNOD1CCKARCCKBREPHX2
SCHEMBL15360227 0.99 GLP1R (0.82) GLP1RNOD1EPHX2
SCHEMBL22030215 0.99 GLP1R (0.82) GLP1RNOD1EPHX2
SCHEMBL13494664 0.99 GLP1R (0.82) GLP1RNOD1EPHX2
SCHEMBL15359921 0.99 GLP1R (0.82) GLP1RNOD1EPHX2
SCHEMBL22648039 0.99 GLP1R (0.82) GLP1RNOD1EPHX2
SCHEMBL15359922 0.99 GLP1R (0.82) GLP1RNOD1EPHX2
SCHEMBL12686714 0.99 GLP1R (0.82) GLP1RNOD1EPHX2
SCHEMBL15360146 0.99 GLP1R (0.79) GLP1RNOD1CCKARCCKBREPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2758426-B1 NOVEL GLUCAGON ANALOGUES NOVO NORDISK AS (DK) 2019-08-07 EP disclosed