SCHEMBL21242749

SCHEMBL21242749

CN[C@@H](CCCCNC(=O)CC[C@H](NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CCC(NC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(=O)O)C(=O)O)C(C)=O

nearest known ligand 0.69

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.69
▸ CCKAR P32238 7/20 0.44
▸ CCKBR P32239 7/20 0.44
▸ FOLH1 Q04609 3/20 0.44
▸ NOD1 Q9Y239 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17127185 1.00 GLP1R (0.69) GLP1RCCKARCCKBRFOLH1NOD1
SCHEMBL19786713 1.00 GLP1R (0.69) GLP1RCCKARCCKBRFOLH1NOD1
SCHEMBL14805474 1.00 GLP1R (0.69) GLP1RCCKARCCKBRFOLH1NOD1
SCHEMBL21242716 1.00 GLP1R (0.69) GLP1RCCKARCCKBRFOLH1NOD1
SCHEMBL21242700 1.00 GLP1R (0.69) GLP1RCCKARCCKBRFOLH1NOD1
SCHEMBL21242874 1.00 GLP1R (0.69) GLP1RCCKARCCKBRFOLH1NOD1
SCHEMBL17127184 1.00 GLP1R (0.69) GLP1RCCKARCCKBRFOLH1NOD1
SCHEMBL21242938 1.00 GLP1R (0.69) GLP1RCCKARCCKBRFOLH1NOD1
SCHEMBL21242892 1.00 GLP1R (0.69) GLP1RCCKARCCKBRFOLH1NOD1
SCHEMBL14998201 1.00 GLP1R (0.69) GLP1RCCKARCCKBRFOLH1NOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2758426-B1 NOVEL GLUCAGON ANALOGUES NOVO NORDISK AS (DK) 2019-08-07 — — EP disclosed
Send feedback