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SCHEMBL21242883

SCHEMBL21242883

CCC[C@H](NC(=O)CCC(NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@H](NC(=O)CCCCCCCCCOc1ccc(C(=O)O)cc1)C(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.58
▸ ITGB3 P05106 2/20 0.47
▸ ITGA2B P08514 2/20 0.47
▸ CCKAR P32238 5/20 0.44
▸ CCKBR P32239 5/20 0.44
▸ TP53 P04637 1/20 0.43
▸ TSHR P16473 1/20 0.43
▸ PLA2G4B P0C869 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2175552 0.97 GLP1R (0.54) GLP1RITGB3ITGA2BTP53TSHR
SCHEMBL18560527 0.97 GLP1R (0.54) GLP1RITGB3ITGA2BTP53TSHR
SCHEMBL12501560 0.96 GLP1R (0.59) GLP1RITGB3ITGA2BCCKARCCKBR
SCHEMBL16455544 0.96 GLP1R (0.63) GLP1RITGB3ITGA2BTP53TSHR
SCHEMBL19152613 0.96 GLP1R (0.63) GLP1RITGB3ITGA2BTP53TSHR
SCHEMBL24652677 0.96 GLP1R (0.59) GLP1RITGB3ITGA2BCCKARCCKBR
SCHEMBL12497136 0.96 GLP1R (0.59) GLP1RITGB3ITGA2BCCKARCCKBR
SCHEMBL20652754 0.96 GLP1R (0.63) GLP1RITGB3ITGA2BTP53TSHR
SCHEMBL12496921 0.96 GLP1R (0.59) GLP1RITGB3ITGA2BCCKARCCKBR
SCHEMBL12496872 0.96 GLP1R (0.59) GLP1RITGB3ITGA2BCCKARCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2758426-B1 NOVEL GLUCAGON ANALOGUES NOVO NORDISK AS (DK) 2019-08-07 — — EP disclosed
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