Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2125331 | 0.91 | S1PR1 (0.84) | S1PR1S1PR5 | |
| SCHEMBL2125026 | 0.91 | S1PR1 (1.00) | S1PR1S1PR5 | |
| SCHEMBL2124326 | 0.90 | S1PR1 (0.83) | S1PR1S1PR5 | |
| Hydrochloric Acid SCHEMBL2122860 | 0.90 | S1PR1 (0.98) | S1PR1S1PR5 | |
| SCHEMBL2125038 | 0.88 | S1PR1 (0.80) | S1PR1S1PR5 | |
| Trifluoroacetic Acid SCHEMBL2125035 | 0.87 | S1PR1 (0.92) | S1PR1S1PR5 | |
| SCHEMBL13012942 | 0.86 | S1PR1 (0.81) | S1PR1S1PR5 | |
| SCHEMBL2130109 | 0.84 | S1PR1 (0.75) | S1PR1S1PR5 | |
| SCHEMBL3424513 | 0.84 | S1PR1 (0.80) | S1PR1S1PR5 | |
| SCHEMBL2130128 | 0.83 | S1PR1 (0.80) | S1PR1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443116-A1 | THIADIAZOLE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF DISORDERS MEDIATED BY SLPL RECEPTORS | Glaxo Group Limited (GB) | 2012-04-25 | — | — | EP | disclosed |
| WO-2010146104-A1 | THIADIAZOLE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF DISORDERS MEDIATED BY SLPL RECEPTORS | GLAXO GROUP LIMITED (GB) | 2010-12-23 | — | — | WO | disclosed |