Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.60 |
| ▸ | REN | P00797 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PEPD | P12955 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | HRH1 | P35367 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21246655 | 1.00 | ACE (0.60) | ACERENKDM4EF2LMNA | |
| SCHEMBL8271441 | 0.95 | ACE (0.55) | ACERENKDM4EF2LMNA | |
| SCHEMBL15854285 | 0.88 | ACE (0.62) | ACERENKDM4EF2LMNA | |
| SCHEMBL5742529 | 0.88 | ACE (0.62) | ACERENKDM4EF2LMNA | |
| SCHEMBL5742535 | 0.88 | ACE (0.62) | ACERENKDM4EF2LMNA | |
| SCHEMBL8096905 | 0.86 | ACE (0.58) | ACERENKDM4EF2LMNA | |
| SCHEMBL8096916 | 0.86 | ACE (0.58) | ACERENKDM4EF2LMNA | |
| SCHEMBL7380841 | 0.85 | ACE (0.59) | ACERENKDM4EF2LMNA | |
| SCHEMBL11581559 | 0.85 | ACE (0.63) | ACERENKDM4EF2LMNA | |
| SCHEMBL11558594 | 0.84 | ACE (0.66) | ACERENKDM4EF2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108017555-B | Beta-hydroxybutyryl-amino acid compound and preparation method and application thereof | 郑州海斯威生物技术有限公司 | 2021-03-26 | — | — | CN | disclosed |
| WO-2019104851-A4 | BETA-HYDROXYBUTYRYL-AMINO ACID COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 刘成 | 2019-08-15 | — | — | WO | disclosed |
| CN-108017555-A | A kind of beta-hydroxy butyryl-amino-acid compound and preparation method and application | 郑州海斯威生物技术有限公司 | 2018-05-11 | — | — | CN | disclosed |