Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2124833 | 1.00 | KDM4E (0.30) | KDM4EMAPTCYP19A1TBXAS1 | |
| SCHEMBL20198577 | 0.94 | KDM4E (0.34) | KDM4EMAPT | |
| SCHEMBL2126830 | 0.94 | KDM4E (0.34) | KDM4EMAPT | |
| SCHEMBL2125868 | 0.94 | KDM4E (0.34) | KDM4EMAPT | |
| SCHEMBL20104757 | 0.94 | KDM4E (0.34) | KDM4EMAPT | |
| SCHEMBL23740127 | 0.94 | KDM4E (0.34) | KDM4EMAPT | |
| SCHEMBL8777072 | 0.94 | KDM4E (0.34) | KDM4EMAPT | |
| SCHEMBL2127065 | 0.94 | KDM4E (0.34) | KDM4EMAPT | |
| SCHEMBL20610083 | 0.94 | KDM4E (0.34) | KDM4EMAPT | |
| SCHEMBL7383849 | 0.94 | KDM4E (0.34) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019046126-A1 | AMINOGLYCOSIDES AND USES THEREOF | ACHAOGEN, INC. (US) | 2019-03-07 | — | — | WO | disclosed |
| EP-2444397-A1 | Heteroaryl-ureas and their use as glucokinase activators | Novo Nordisk A/S (DK) | 2012-04-25 | — | — | EP | disclosed |