Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 15/20 | 0.42 |
| ▸ | SSTR5 | P35346 | 4/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21248718 | 1.00 | RET (0.42) | RETSSTR5SLC22A12 | |
| SCHEMBL21248768 | 0.87 | RET (0.47) | RET | |
| SCHEMBL21248767 | 0.87 | RET (0.47) | RET | |
| SCHEMBL21248831 | 0.84 | RET (0.43) | RET | |
| SCHEMBL21248829 | 0.84 | RET (0.43) | RET | |
| SCHEMBL29653449 | 0.83 | RET (0.39) | RET | |
| SCHEMBL21248843 | 0.80 | KDM4D (0.45) | RETSSTR5 | |
| SCHEMBL21248845 | 0.80 | KDM4D (0.45) | RETSSTR5 | |
| SCHEMBL21248840 | 0.78 | RET (0.36) | RET | |
| SCHEMBL21248841 | 0.78 | RET (0.36) | RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752498-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2020-12-23 | — | — | EP | disclosed |
| WO-2019157458-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2019-08-15 | — | — | WO | disclosed |