Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20031344 | 0.71 | SMN1; SMN2 (0.45) | HTTTSHRALDH1A1SMN1; SMN2FAAH | |
| SCHEMBL19494552 | 0.70 | HTT (0.39) | HTTTSHRALDH1A1SMN1; SMN2FAAH | |
| SCHEMBL18731318 | 0.68 | HTT (0.44) | HTTTSHRALDH1A1SMN1; SMN2FAAH | |
| SCHEMBL25927977 | 0.67 | POLB (0.34) | HTTTSHRPOLBMAPT | |
| SCHEMBL2586150 | 0.66 | HTT (0.45) | HTTTSHRALDH1A1SMN1; SMN2FAAH | |
| SCHEMBL27262765 | 0.65 | SMN1; SMN2 (0.46) | HTTTSHRSMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL19689876 | 0.63 | HTT (0.39) | HTTTSHRALDH1A1SMN1; SMN2FAAH | |
| SCHEMBL8252369 | 0.62 | — | — | |
| SCHEMBL14539018 | 0.62 | SMN1; SMN2 (0.43) | HTTTSHRALDH1A1SMN1; SMN2FAAH | |
| SCHEMBL968486 | 0.62 | HTT (0.50) | HTTTSHRALDH1A1SMN1; SMN2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230289-B1 | 7-(MORPHOLINYL)-2-(N-PIPERAZINYL) METHYL THIENO [2, 3-C]PYRIDINE DERIVATIVES AS ANTICANCER DRUGS | NATCO PHARMA LTD (IN) | 2019-08-14 | — | — | EP | disclosed |