Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 18/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 15/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2127953 | 0.92 | HCRTR1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL2126430 | 0.92 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL2128479 | 0.92 | HCRTR1 (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL2127018 | 0.92 | HCRTR1 (0.38) | HCRTR1HCRTR2 | |
| SCHEMBL981543 | 0.90 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL2128566 | 0.90 | HCRTR1 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL2125110 | 0.88 | HCRTR1 (0.35) | HCRTR1HCRTR2 | |
| SCHEMBL2127245 | 0.87 | HCRTR1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL2127802 | 0.85 | HCRTR1 (0.38) | HCRTR1HCRTR2 | |
| SCHEMBL2127231 | 0.85 | HCRTR1 (0.39) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247586-B1 | 2-AZA-BICYCLO[2.2.1]HEPTANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-04-25 | — | — | EP | claimed |