Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29579532 | 0.92 | USP2 (0.56) | SMN1; SMN2USP2RECQLMGLLEPHX2 | |
| SCHEMBL31197156 | 0.90 | USP2 (0.53) | SMN1; SMN2USP2RECQLMGLLEPHX2 | |
| SCHEMBL714947 | 0.90 | USP2 (0.53) | SMN1; SMN2USP2RECQLMGLLEPHX2 | |
| SCHEMBL22297500 | 0.87 | USP2 (0.50) | SMN1; SMN2USP2RECQLMGLLEPHX2 | |
| SCHEMBL19320633 | 0.87 | USP2 (0.50) | SMN1; SMN2USP2RECQLMGLLEPHX2 | |
| SCHEMBL2960741 | 0.86 | USP2 (0.51) | SMN1; SMN2USP2RECQLMGLLEPHX2 | |
| SCHEMBL993522 | 0.86 | USP2 (0.49) | SMN1; SMN2USP2RECQLMGLLEPHX2 | |
| SCHEMBL24692803 | 0.85 | SMN1; SMN2 (0.59) | SMN1; SMN2USP2RECQLEPHX2SCD5 | |
| SCHEMBL31309984 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2USP2RECQLMGLLEPHX2 | |
| SCHEMBL24379120 | 0.85 | USP2 (0.48) | SMN1; SMN2USP2RECQLMGLLEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3113780-B1 | HIV PROTEASE INHIBITORS | MERCK SHARP & DOHME (US) | 2019-08-14 | — | — | EP | disclosed |