Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.45 |
| ▸ | KDM5C | P41229 | 3/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 7/20 | 0.42 |
| ▸ | KDM5A | P29375 | 4/20 | 0.42 |
| ▸ | HRH1 | P35367 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.40 |
| ▸ | KDM4A | O75164 | 3/20 | 0.40 |
| ▸ | KDM6B | O15054 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21257791 | 0.89 | KDM5C (0.43) | KDM4CKDM5CKDM5BKDM5AKDM2B | |
| SCHEMBL21257707 | 0.89 | KDM5C (0.43) | KDM4CKDM5CKDM5BKDM5AKDM2B | |
| SCHEMBL21257674 | 0.88 | KDM5B (0.45) | KDM4CKDM5CKDM5BKDM5AHRH1 | |
| SCHEMBL21257593 | 0.88 | KDM4C (0.43) | KDM4CKDM5CKDM5BKDM5AKDM2B | |
| SCHEMBL21257572 | 0.88 | KDM4C (0.43) | KDM4CKDM5CKDM5BKDM5AKDM2B | |
| SCHEMBL21257570 | 0.88 | KDM4C (0.43) | KDM4CKDM5CKDM5BKDM5AHRH1 | |
| SCHEMBL21257795 | 0.88 | KDM4C (0.43) | KDM4CKDM5CKDM5BKDM5AKDM2B | |
| SCHEMBL21257742 | 0.88 | KDM5C (0.44) | KDM4CKDM5CKDM5BKDM5AKDM2B | |
| SCHEMBL21257590 | 0.88 | KDM4C (0.44) | KDM4CKDM5CKDM5BKDM5AKDM2B | |
| SCHEMBL21257739 | 0.86 | KDM4C (0.43) | KDM4CKDM5CKDM5BKDM5AKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019154261-A1 | PYRIDINE DERIVATIVE RELATED TO KMD5 PATHWAY | 南京明德新药研发股份有限公司 | 2019-08-15 | — | — | WO | disclosed |