Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 6/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21258941 | 0.93 | PTGIR (0.44) | PTGIRPTGDRACHECKS1BSKP1 | |
| SCHEMBL21258988 | 0.92 | CKS1B (0.44) | PTGIRPTGDRCKS1BSKP1SKP2 | |
| SCHEMBL21258952 | 0.92 | PTGIR (0.37) | PTGIRPTGDRCKS1BSKP1SKP2 | |
| SCHEMBL21258969 | 0.92 | PTGIR (0.43) | PTGIRPTGDRCKS1BSKP1SKP2 | |
| SCHEMBL21258896 | 0.90 | PTGIR (0.54) | PTGIRPTGDRACHEFFAR1 | |
| SCHEMBL21258862 | 0.90 | PTGIR (0.44) | PTGIRPTGDRCKS1BSKP1SKP2 | |
| SCHEMBL21258854 | 0.90 | PTGIR (0.42) | PTGIRPTGDRCKS1BSKP1SKP2 | |
| SCHEMBL21258657 | 0.88 | PTGIR (0.43) | PTGIRPTGDRCKS1BSKP1SKP2 | |
| SCHEMBL21258986 | 0.87 | PTGIR (0.42) | PTGIRPTGDRCKS1BSKP1SKP2 | |
| SCHEMBL21258912 | 0.87 | PTGIR (0.42) | PTGIRPTGDRCKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210087168-A1 | PROSTACYCLIN RECEPTOR AGONIST | MEDSHINE DISCOVERY INC. (CN) | 2021-03-25 | — | — | US | disclosed |
| EP-3750879-A1 | PROSTACYCLIN RECEPTOR AGONIST | Medshine Discovery Inc. (CN) | 2020-12-16 | — | — | EP | disclosed |
| WO-2019154363-A1 | PROSTACYCLIN RECEPTOR AGONIST | 南京明德新药研发有限公司 | 2019-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210087168-A1 | PROSTACYCLIN RECEPTOR AGONIST | PTGIR, TBXA2R, PTGFR | PTGIR 1/4885PTGDR 9/4885ACHE 4008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.