Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 7/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2126334 | 1.00 | CHRM3 (0.52) | CHRM3CHRNA7CHRM2CHRM1KDM4E | |
| SCHEMBL5712869 | 0.76 | CHRM2 (0.53) | CHRM3CHRNA7CHRM2CHRM1 | |
| SCHEMBL327105 | 0.73 | CYP2B6 (0.42) | CHRM3KDM4EALDH1A1 | |
| SCHEMBL2127690 | 0.73 | CYP2B6 (0.45) | CHRM3KDM4EALDH1A1POLB | |
| SCHEMBL2128441 | 0.73 | CYP2B6 (0.45) | CHRM3KDM4EALDH1A1POLB | |
| SCHEMBL4971345 | 0.70 | CHRNA7 (0.56) | CHRM3CHRNA7CHRM2CHRM1KDM4E | |
| SCHEMBL2128977 | 0.70 | CHRM3 (0.98) | CHRM3CHRM2CHRM1 | |
| SCHEMBL2127514 | 0.70 | CHRM3 (0.98) | CHRM3CHRM2CHRM1 | |
| SCHEMBL1683013 | 0.70 | CHRM3 (0.98) | CHRM3CHRM2CHRM1 | |
| SCHEMBL3306597 | 0.70 | CHRM3 (0.98) | CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121137-B1 | QUINUCLIDINOL DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2012-04-25 | — | — | EP | disclosed |