Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 18/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21247352 | 0.88 | CFTR (0.51) | CFTRALDH1A1LMNAMAPTHPGD | |
| SCHEMBL22696748 | 0.81 | CFTR (0.53) | CFTRALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL21247096 | 0.74 | PTPN1 (0.53) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL21247367 | 0.71 | CFTR (0.52) | CFTRALDH1A1LMNAMAPTHPGD | |
| SCHEMBL22680877 | 0.70 | PTPN1 (0.48) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL21250161 | 0.69 | SMN1; SMN2 (0.65) | CFTRALDH1A1LMNAMAPTHPGD | |
| SCHEMBL21260703 | 0.68 | CFTR (0.54) | CFTR | |
| SCHEMBL21018758 | 0.68 | CFTR (0.55) | CFTR | |
| SCHEMBL21248056 | 0.67 | CFTR (0.59) | CFTRALDH1A1LMNAMAPTHPGD | |
| SCHEMBL20468190 | 0.64 | CFTR (0.69) | CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019154949-A1 | FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO PHARMA (FR) | 2019-08-15 | — | — | WO | disclosed |