SCHEMBL2126140

SCHEMBL2126140

C=CC(=O)NCCNC(N)=O

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.54
ALDH1A1 P00352 3/20 0.54
TDP1 Q9NUW8 2/20 0.54
MAPK1 P28482 1/20 0.54
ZDHHC20 Q5W0Z9 1/20 0.50
ZDHHC2 Q9UIJ5 1/20 0.50
FGFR4 P22455 1/20 0.39
TGM2 P21980 3/20 0.37
GAA P10253 1/20 0.36
MAPT P10636 2/20 0.34
CACNA1B Q00975 1/20 0.34
APBA1 Q02410 1/20 0.34
BTK Q06187 3/20 0.32
LMNA P02545 1/20 0.31
KMT2A Q03164 1/20 0.31
MTNR1A P48039 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylamide SCHEMBL7163814 0.88 TSHR (0.56) TSHRALDH1A1TDP1MAPK1ZDHHC20
SCHEMBL167051 0.87 TSHR (0.68) TSHRALDH1A1TDP1MAPK1ZDHHC20
SCHEMBL10952688 0.87 TSHR (0.68) TSHRALDH1A1TDP1MAPK1ZDHHC20
Water SCHEMBL28173091 0.85 TSHR (0.65) TSHRALDH1A1TDP1MAPK1ZDHHC20
SCHEMBL30705730 0.82 TSHR (0.50) TSHRALDH1A1TDP1MAPK1ZDHHC20
SCHEMBL38665296 0.82 TSHR (0.50) TSHRALDH1A1TDP1MAPK1ZDHHC20
SCHEMBL26027036 0.81
SCHEMBL12490785 0.81 TSHR (0.76) TSHRALDH1A1TDP1MAPK1ZDHHC20
SCHEMBL21408788 0.80 TSHR (0.48) TSHRALDH1A1TDP1MAPK1ZDHHC20
SCHEMBL9238864 0.80 TDP1 (0.50) TSHRALDH1A1TDP1MAPK1ZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108250159-B Urea compound, preparation method and application thereof 深圳微芯生物科技股份有限公司 2023-07-11 CN claimed
US-6485601-B1 Water based construction adhesive having improved moisture resistance useful for binding two substrates BASF CORPORATION 2002-11-26 US claimed
CN-112638872-B Pigment dispersants 巴斯夫涂料有限公司 2024-07-26 CN disclosed
EP-1926577-B1 USE OF A LATEX COMPOSITION HAVING AT LEAST ONE UREIDO FUNCTION FOR ADHERING TO WOOD LAPEYRE (FR) 2013-01-02 EP disclosed
EP-2442644-A1 OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE Bikam Pharmaceuticals, Inc. (US) 2012-04-25 EP disclosed
WO-2012049453-A2 COMPOSITIONS FOR TOPICAL APPLICATIONS VECTUM PHARMA S.L. (ES) 2012-04-19 WO disclosed
US-20080311415-A1 Use of a Latex Composition Having at Least One Ureido Function For Adhering to Wood LAPEYRE (FR) 2008-12-18 US disclosed
CN-101321607-A Use of aqueous dispersion in surface treatment of wood, where dispersion comprises latex made of polymerization of monomer mixture emulsion comprising monomers e.g. butadiene, and another monomers lik RHODIA RECH S TECH (FR) 2008-12-10 CN disclosed
EP-1926577-A1 USE OF A LATEX COMPOSITION HAVING AT LEAST ONE UREIDO FUNCTION FOR ADHERING TO WOOD Lapeyre (FR) 2008-06-04 EP disclosed
WO-2007026074-A1 USE OF A LATEX COMPOSITION HAVING AT LEAST ONE UREIDO FUNCTION FOR ADHERING TO WOOD LAPEYRE (FR) 2007-03-08 WO disclosed
US-6485601-B1 Water based construction adhesive having improved moisture resistance useful for binding two substrates BASF CORPORATION 2002-11-26 US disclosed
US-5202375-A Containing surfactant ROHM AND HAAS COMPANY (US) 1993-04-13 US disclosed
US-5185397-A Emulsion of water, a surfactant and a polymer of ethylhexyl acrylate, acrylonitrile, an olefinic carboxylic acid and a crosslinking agent ROHM AND HAAS COMPANY (US) 1993-02-09 US disclosed
EP-0489109-A1 WATER-BASED VARNISHES. UNION OIL CO (US) 1992-06-10 EP disclosed
US-5118749-A Copolymerizing acylate monomers; further polymerizing in presence of chain transfer agent UNION OIL COMPANY OF CALIFORNIA (US) 1992-06-02 US disclosed
US-5116901-A Latex-lipophilic polymer graft polymerization process UNION OIL COMPANY OF CALIFORNIA (US) 1992-05-26 US disclosed
EP-0484399-A1 WATER-RESISTANT POLYMERIC EMULSIONS ROHM AND HAAS COMPANY (US) 1992-05-13 EP disclosed
WO-1991002775-A1 WATER-BASED VARNISHES UNION OIL COMPANY OF CALIFORNIA (US) 1991-03-07 WO disclosed
WO-1991002007-A1 WATER-RESISTANT POLYMERIC EMULSIONS UNION OIL COMPANY OF CALIFORNIA (US) 1991-02-21 WO disclosed
US-4284718-A ADDITION POLYMERS AND A DISULFIDE COMPOUND AGFA-GEVAERT AG (DE) 1981-08-18 US disclosed