⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL872865 | 0.72 | — | — | |
| SCHEMBL6739445 | 0.72 | — | — | |
| SCHEMBL12483162 | 0.63 | — | — | |
| SCHEMBL7086866 | 0.61 | — | — | |
| SCHEMBL1593092 | 0.60 | — | — | |
| SCHEMBL1035336 | 0.56 | — | — | |
| SCHEMBL586833 | 0.54 | — | — | |
| SCHEMBL5597052 | 0.54 | — | — | |
| SCHEMBL775329 | 0.48 | — | — | |
| Hydrochloric Acid SCHEMBL27779692 | 0.46 | IDH1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1061065-B1 | Methods for producing cyclopropane carboxylates | SUMITOMO CHEMICAL CO (JP) | 2006-08-23 | — | — | EP | claimed |
| EP-1203760-B1 | Method for producing cyclopropanecarboxylates | SUMITOMO CHEMICAL CO (JP) | 2005-04-13 | — | — | EP | claimed |
| US-6706910-B2 | BY TRANSESTERIFICATION OF A CYCLOPROPANECARBOXYLATE AND A MONOHYDROXY COMPOUND IN THE PRESENCE OF A LITHIUM ALKOXIDE OR LITHIUM ARYLOXIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-03-16 | — | — | US | claimed |
| US-6531626-B1 | Transesterification in the presence of a samarium alkoxide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-03-11 | — | — | US | claimed |
| EP-0992479-B1 | Method for producing cyclopropanecarboxylates | SUMITOMO CHEMICAL CO (JP) | 2003-01-02 | — | — | EP | claimed |
| US-6441220-B1 | ESTERIFICATION WITH ALCOHOL IN PRESENCE OF BASIC CATALYSTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-08-27 | — | — | US | claimed |
| EP-1203760-A1 | Method for producing cyclopropanecarboxylates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-05-08 | — | — | EP | claimed |
| US-20020052525-A1 | Method for producing cyclopropanecarboxylates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-05-02 | — | — | US | claimed |
| EP-1061065-A2 | Methods for producing cyclopropane carboxylates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-12-20 | — | — | EP | claimed |
| EP-0992479-A1 | Method for producing cyclopropanecarboxylates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-04-12 | — | — | EP | claimed |
| US-20230233551-A1 | COMPOSITIONS AND METHODS FOR TREATMENT | CITIBANK, N.A., AS NOTES COLLATERAL AGENT | 2023-07-27 | — | — | US | disclosed |
| US-20210338839-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DIABETIC RETINOPATHY | NOVARTIS AG (CH) | 2021-11-04 | — | — | US | disclosed |
| EP-3797775-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DIABETIC RETINOPATHY | Novartis AG (CH) | 2021-03-31 | — | — | EP | disclosed |
| US-10960087-B2 | Compositions and methods for treatment of diabetic retinopathy | NOVARTIS AG (CH) | 2021-03-30 | — | — | US | disclosed |
| EP-3167886-B1 | COMPOSITIONS AND METHODS FOR TREATMENT OF MACULAR EDEMA | NOVARTIS AG (CH) | 2020-08-05 | — | — | EP | disclosed |
| WO-2002059114-A1 | LFA-1 ANTAGONIST COMPOUNDS | GENENTECH, INC. (US) | 2002-08-01 | — | — | WO | disclosed |
| EP-1203760-A1 | Method for producing cyclopropanecarboxylates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-05-08 | — | — | EP | disclosed |
| US-20020052525-A1 | Method for producing cyclopropanecarboxylates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-05-02 | — | — | US | disclosed |
| EP-1061065-A2 | Methods for producing cyclopropane carboxylates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-12-20 | — | — | EP | disclosed |
| EP-0992479-A1 | Method for producing cyclopropanecarboxylates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-04-12 | — | — | EP | disclosed |