⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20648710 | 0.85 | — | — | |
| SCHEMBL14679697 | 0.76 | — | — | |
| SCHEMBL12457880 | 0.74 | — | — | |
| SCHEMBL12457631 | 0.74 | — | — | |
| SCHEMBL18911774 | 0.74 | — | — | |
| SCHEMBL1231674 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL5531798 | 0.72 | — | — | |
| SCHEMBL678724 | 0.69 | — | — | |
| SCHEMBL24951564 | 0.69 | CYP2D6 (0.39) | — | |
| SCHEMBL22962150 | 0.69 | CYP2D6 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752498-B1 | SOMATOSTATIN MODULATORS AND USES THEREOF | CRINETICS PHARMACEUTICALS INC (US) | 2023-06-28 | — | — | EP | disclosed |
| WO-2019157458-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2019-08-15 | — | — | WO | disclosed |