Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 5/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 2/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21263357 | 0.98 | CYP1A1 (0.38) | CYP1A1CYP1B1LIMK1HTR2BHTR5A | |
| SCHEMBL21263479 | 0.96 | CYP1A1 (0.39) | CYP1A1CYP1B1LIMK1HTR2BHTR5A | |
| SCHEMBL19936968 | 0.96 | CYP1A1 (0.37) | CYP1A1CYP1B1LIMK1HTR2BHTR5A | |
| SCHEMBL19936947 | 0.96 | CYP1A1 (0.38) | CYP1A1CYP1B1LIMK1HTR2BHTR5A | |
| SCHEMBL21263330 | 0.95 | CYP1A1 (0.39) | CYP1A1CYP1B1LIMK1ROCK1MEN1 | |
| SCHEMBL19937279 | 0.94 | CYP1A1 (0.38) | CYP1A1CYP1B1LIMK1HTR2BHTR5A | |
| SCHEMBL19937278 | 0.94 | CYP1A1 (0.41) | CYP1A1CYP1B1LIMK1ROCK1MEN1 | |
| SCHEMBL19937163 | 0.94 | TSHR (0.37) | CYP1A1CYP1B1LIMK1LIMK2MEN1 | |
| SCHEMBL21263342 | 0.92 | LIMK1 (0.38) | LIMK1HTR2BHTR5AROCK1LIMK2 | |
| SCHEMBL19937235 | 0.91 | CYP1A1 (0.36) | CYP1A1CYP1B1LIMK1HTR2BHTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190248804-A1 | SPECIFICALLY SUBSTITUTED AZA-DIBENZOFURANS AND AZA-DIBENZOTHIOPHENES FOR ORGANIC ELECTRONIC DEVICES | IDEMITSU KOSAN CO., LTD. (JP) | 2019-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190248804-A1 | SPECIFICALLY SUBSTITUTED AZA-DIBENZOFURANS AND AZA-DIBENZOTHIOPHENES FOR ORGANIC ELECTRONIC DEVICES | CDY1; CDY1B, CDYL, CBX8 | CYP1A1 824/4885CYP1B1 412/4885LIMK1 3482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.