⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1149312 | 1.00 | — | — | |
| SCHEMBL499144 | 0.71 | — | — | |
| SCHEMBL4121888 | 0.69 | — | — | |
| SCHEMBL6971707 | 0.65 | — | — | |
| SCHEMBL6959895 | 0.63 | — | — | |
| SCHEMBL7453587 | 0.62 | — | — | |
| SCHEMBL10304149 | 0.61 | — | — | |
| SCHEMBL2493288 | 0.61 | — | — | |
| SCHEMBL12826483 | 0.61 | — | — | |
| SCHEMBL2995766 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240182463-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO., LTD. (JP) | 2024-06-06 | — | — | US | disclosed |
| US-20230117695-A1 | ARENAVIRUS GROWTH INHIBITOR COMPRISING POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2023-04-20 | — | — | US | disclosed |
| US-11492352-B2 | Arenavirus growth inhibitor comprising polycyclic carbamoylpyridone derivative | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2022-11-08 | — | — | US | disclosed |
| US-20210292321-A1 | ARENAVIRUS GROWTH INHIBITOR COMPRISING POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2021-09-23 | — | — | US | disclosed |
| EP-3815689-A1 | ARENAVIRUS GROWTH INHIBITOR COMPRISING POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE | National University Corporation Hokkaido University (JP) | 2021-05-05 | — | — | EP | disclosed |
| US-20200339565-A1 | PRODRUG SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2020-10-29 | — | — | US | disclosed |
| US-20190248785-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO., LTD. (JP) | 2019-08-15 | — | — | US | disclosed |
| US-10202379-B2 | Substituted polycyclic carbamoyl pyridone derivative prodrug | SHIONOGI & CO., LTD. (JP) | 2019-02-12 | — | — | US | disclosed |
| EP-2620436-B1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO (JP) | 2018-05-09 | — | — | EP | disclosed |
| EP-2444400-B1 | SUBSTITUTED POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE | SHIONOGI & CO (JP) | 2018-03-28 | — | — | EP | disclosed |
| WO-2000078712-A1 | SUBSTITUTED ARYLMALONIC ACID DINITRILES AS INTERMEDIATES FOR THE PREPARTION OF HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-12-28 | — | — | WO | disclosed |
| WO-2000078881-A2 | PROCESS FOR THE PREPARATION OF HERBICIDAL DERIVATIVES | SYGENTA PARTICIPATIONS AG (CH) | 2000-12-28 | — | — | WO | disclosed |
| US-6017467-A | HEAT AND CHEMICAL RESISTANCE | CHISSO CORPORATION (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0966461-A1 | PYRAZOLE DERIVATIVES AS HERBICIDES | Novartis AG (CH) | 1999-12-29 | — | — | EP | disclosed |
| WO-1999052893-A1 | N-PYRIDONYL HERBICIDES | NOVARTIS AG (CH) | 1999-10-21 | — | — | WO | disclosed |
| EP-0929543-A1 | HERBICIDAL COMPOSITION | Novartis AG (CH) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998042698-A1 | PYRAZOLE DERIVATIVES AS HERBICIDES | NOVARTIS AG (CH) | 1998-10-01 | — | — | WO | disclosed |
| WO-1998013361-A1 | HERBICIDAL COMPOSITION | NOVARTIS AG (CH) | 1998-04-02 | — | — | WO | disclosed |
| CN-1174832-A | Propiolonitrile derivatives and liquid crystal compositions comprising the same | CHISSO CORP (JP) | 1998-03-04 | — | — | CN | disclosed |
| EP-0816332-A1 | Propiolonitrile derivatives and liquid crystal compositions comprising the same | Chisso Corporation (JP) | 1998-01-07 | — | — | EP | disclosed |