Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10451936 | 1.00 | CYP3A4 (0.58) | CYP3A4CYP2C9RECQLAKR1C3GRIK1 | |
| SCHEMBL1716474 | 1.00 | CYP3A4 (0.58) | CYP3A4CYP2C9RECQLAKR1C3GRIK1 | |
| SCHEMBL2138074 | 0.89 | CYP3A4 (0.62) | CYP3A4CYP2C9RECQLAKR1C3GRIK1 | |
| SCHEMBL10410676 | 0.86 | CYP3A4 (0.54) | CYP3A4CYP2C9RECQLAKR1C3GRIK1 | |
| SCHEMBL28317118 | 0.86 | RECQL (0.49) | CYP3A4CYP2C9RECQLAKR1C3GRIK1 | |
| SCHEMBL10409218 | 0.84 | CYP3A4 (0.53) | CYP3A4CYP2C9RECQLAKR1C3GRIK1 | |
| SCHEMBL14659091 | 0.84 | GRIK1 (0.68) | CYP3A4CYP2C9AKR1C3GRIK1AKR1C1 | |
| SCHEMBL10451720 | 0.83 | RECQL (0.50) | CYP3A4CYP2C9RECQLAKR1C3MEN1 | |
| SCHEMBL10451721 | 0.83 | RECQL (0.50) | CYP3A4CYP2C9RECQLAKR1C3MEN1 | |
| SCHEMBL1716809 | 0.82 | CYP3A4 (0.54) | CYP3A4CYP2C9RECQLAKR1C3GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200354321-A1 | NEW PYRIDINE CARBOXAMIDES | BASF SE (DE) | 2020-11-12 | — | — | US | disclosed |
| WO-2019154663-A1 | NEW PYRIDINE CARBOXAMIDES | BASF SE (DE) | 2019-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354321-A1 | NEW PYRIDINE CARBOXAMIDES | COX4I1, NQO2, NDUFS5 | CYP3A4 115/4885CYP2C9 135/4885RECQL 2562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.