Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.47 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ITK | Q08881 | 7/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21265764 | 0.94 | EHMT2 (0.46) | EHMT2EHMT1USP2LMNAABCC4 | |
| SCHEMBL25887858 | 0.89 | EHMT2 (0.47) | EHMT2EHMT1USP2LMNAABCC4 | |
| SCHEMBL23619291 | 0.88 | EHMT2 (0.44) | EHMT2EHMT1USP2LMNAABCC4 | |
| SCHEMBL21265754 | 0.87 | EHMT2 (0.43) | EHMT2EHMT1USP2LMNAABCC4 | |
| Hydrochloric Acid SCHEMBL23610932 | 0.87 | EHMT2 (0.46) | EHMT2EHMT1USP2LMNAABCC4 | |
| SCHEMBL21265766 | 0.86 | EHMT2 (0.42) | EHMT2EHMT1USP2LMNAABCC4 | |
| SCHEMBL23610928 | 0.86 | EHMT2 (0.42) | EHMT2EHMT1USP2LMNAABCC4 | |
| SCHEMBL21265743 | 0.85 | EHMT2 (0.51) | EHMT2EHMT1USP2LMNAABCC4 | |
| SCHEMBL25889293 | 0.85 | EHMT2 (0.42) | EHMT2EHMT1USP2LMNAABCC4 | |
| SCHEMBL23619186 | 0.85 | EHMT2 (0.46) | EHMT2EHMT1USP2LMNAABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019157338-A1 | MEBENDAZOLE PRODRUGS WITH ENHANCED SOLUBILITY AND ORAL BIOAVAILABILITY | THE JOHNS HOPKINS UNIVERSITY (US) | 2019-08-15 | — | — | WO | disclosed |