Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 14/20 | 0.48 |
| ▸ | HCRTR2 | O43614 | 10/20 | 0.39 |
| ▸ | KIT | P10721 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL981982 | 0.81 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL981979 | 0.81 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL984406 | 0.81 | HCRTR1 (0.53) | HCRTR1HCRTR2 | |
| SCHEMBL983527 | 0.79 | HCRTR1 (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL982579 | 0.79 | HCRTR1 (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL984618 | 0.79 | HCRTR1 (0.55) | HCRTR1HCRTR2 | |
| SCHEMBL2126786 | 0.79 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL982926 | 0.79 | HCRTR1 (0.44) | HCRTR1HCRTR2 | |
| SCHEMBL983211 | 0.78 | HCRTR1 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL984261 | 0.78 | HCRTR1 (0.58) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247586-B1 | 2-AZA-BICYCLO[2.2.1]HEPTANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-04-25 | — | — | EP | disclosed |