Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21268207 | 0.90 | ELANE (0.53) | ELANEKDM1ACA2MAPKAPK2 | |
| SCHEMBL21268208 | 0.88 | ELANE (0.43) | ELANELMNAKMT2ACYP1A2KDM1A | |
| SCHEMBL21268440 | 0.85 | ELANE (0.43) | ELANEKDM1ACA2MAPKAPK2 | |
| SCHEMBL21268199 | 0.84 | ELANE (0.47) | ELANEKDM1ACA2KDM4E | |
| SCHEMBL21268205 | 0.84 | ELANE (0.51) | ELANELMNAKMT2AMEN1KDM1A | |
| SCHEMBL21268324 | 0.84 | ELANE (0.42) | ELANELMNAKMT2AMEN1CYP1A2 | |
| SCHEMBL21268359 | 0.84 | ELANE (0.42) | ELANEKDM1ACA2GPR119 | |
| SCHEMBL21268213 | 0.83 | ELANE (0.44) | ELANEKDM1ACA2 | |
| SCHEMBL21268164 | 0.82 | ELANE (0.49) | ELANEKDM1ACA2 | |
| SCHEMBL21268361 | 0.81 | ELANE (0.47) | ELANELMNAKDM1ACA2MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-B1 | HERBICIDAL AND FUNGICIDAL 3-PHENYLISOXAZOLIN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2019-08-21 | — | — | EP | disclosed |