Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL982244 | 0.87 | HCRTR1 (0.45) | HCRTR1KCNK3KCNK9HCRTR2 | |
| SCHEMBL2127013 | 0.85 | HCRTR1 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL2128566 | 0.85 | HCRTR1 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL2128082 | 0.80 | HCRTR1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL2127953 | 0.80 | HCRTR1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL2126430 | 0.79 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL2127616 | 0.79 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL2127511 | 0.78 | HCRTR1 (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL2127635 | 0.78 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL2127018 | 0.78 | HCRTR1 (0.38) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247586-B1 | 2-AZA-BICYCLO[2.2.1]HEPTANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-04-25 | — | — | EP | claimed |