Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15611604 | 1.00 | TSHR (0.42) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL12757015 | 1.00 | TSHR (0.42) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL28448373 | 1.00 | TSHR (0.42) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL27441419 | 1.00 | TSHR (0.42) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL15611606 | 1.00 | TSHR (0.42) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL212161 | 1.00 | TSHR (0.42) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL212160 | 1.00 | TSHR (0.42) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL212744 | 1.00 | TSHR (0.42) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL212125 | 0.98 | — | — | |
| SCHEMBL212124 | 0.98 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077941-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2012-03-29 | — | — | US | claimed |
| US-8088868-B2 | oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis | BRIDGESTONE CORPORATION (JP) | 2012-01-03 | — | — | US | claimed |
| US-20080146745-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2008-06-19 | — | — | US | claimed |
| US-5675038-A | Lithium and amine dissolving metal reduction | ALLERGAN (US) | 1997-10-07 | — | — | US | claimed |
| US-8541509-B2 | Polymers functionalized with protected oxime compounds | BRIDGESTONE CORPORATION (JP) | 2013-09-24 | — | — | US | disclosed |
| US-20120077941-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2012-03-29 | — | — | US | disclosed |
| US-8088868-B2 | oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis | BRIDGESTONE CORPORATION (JP) | 2012-01-03 | — | — | US | disclosed |
| US-20080146745-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2008-06-19 | — | — | US | disclosed |
| EP-0912465-B1 | IMPROVED LITHIUM AND AMINE DISSOLVING METAL REDUCTION | ALLERGAN SALES INC (US) | 2001-04-04 | — | — | EP | disclosed |
| EP-0912465-A1 | IMPROVED LITHIUM AND AMINE DISSOLVING METAL REDUCTION | Allergan Sales, Inc. (US) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998003451-A1 | IMPROVED LITHIUM AND AMINE DISSOLVING METAL REDUCTION | ALLERGAN SALES, INC. (US) | 1998-01-29 | — | — | WO | disclosed |
| US-5675038-A | Lithium and amine dissolving metal reduction | ALLERGAN (US) | 1997-10-07 | — | — | US | disclosed |