Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21277327 | 0.98 | KDM4E (0.41) | KDM4EGAAHTTLMNASMN1; SMN2 | |
| SCHEMBL8159587 | 0.96 | KDM4E (0.42) | KDM4EGAAHTTLMNASMN1; SMN2 | |
| SCHEMBL9335635 | 0.95 | KDM4E (0.41) | KDM4EGAAHTTLMNASMN1; SMN2 | |
| SCHEMBL8639372 | 0.95 | KDM4E (0.41) | KDM4EGAAHTTLMNASMN1; SMN2 | |
| SCHEMBL8146536 | 0.81 | KDM4E (0.42) | KDM4EGAAHTTLMNASMN1; SMN2 | |
| SCHEMBL18412107 | 0.78 | KDM4E (0.37) | KDM4EGAAHTTLMNASMN1; SMN2 | |
| SCHEMBL19230192 | 0.77 | HTT (0.32) | KDM4EGAAHTTSMN1; SMN2ALOX15 | |
| SCHEMBL8160677 | 0.77 | KDM4E (0.48) | KDM4EGAALMNANPC1RAB9A | |
| SCHEMBL9443659 | 0.76 | KDM4E (0.38) | KDM4EGAAHTTLMNASMN1; SMN2 | |
| SCHEMBL9335973 | 0.76 | CYP1A2 (0.41) | KDM4EGAAHTTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3527576-A1 | PROPYL-BRIDGED DIPHOSPHINE LIGANDS FOR ALKOXYCARBONYLATION | Evonik Degussa GmbH (DE) | 2019-08-21 | — | — | EP | disclosed |