Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 17/20 | 0.59 |
| ▸ | HCRTR2 | O43614 | 16/20 | 0.59 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2127208 | 0.95 | HCRTR1 (0.60) | HCRTR1HCRTR2 | |
| SCHEMBL985931 | 0.94 | HCRTR1 (0.61) | HCRTR1HCRTR2RORC | |
| SCHEMBL983717 | 0.92 | HCRTR1 (0.58) | HCRTR1HCRTR2 | |
| SCHEMBL981779 | 0.92 | HCRTR1 (0.65) | HCRTR1HCRTR2 | |
| SCHEMBL2126428 | 0.92 | HCRTR1 (0.58) | HCRTR1HCRTR2 | |
| SCHEMBL983694 | 0.90 | HCRTR1 (0.61) | HCRTR1HCRTR2 | |
| SCHEMBL2128299 | 0.90 | HCRTR1 (0.60) | HCRTR1HCRTR2 | |
| SCHEMBL983220 | 0.89 | HCRTR1 (0.75) | HCRTR1HCRTR2 | |
| SCHEMBL981533 | 0.89 | HCRTR1 (0.63) | HCRTR1HCRTR2 | |
| SCHEMBL2127973 | 0.89 | HCRTR1 (0.63) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247586-B1 | 2-AZA-BICYCLO[2.2.1]HEPTANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-04-25 | — | — | EP | disclosed |