SCHEMBL212780

SCHEMBL212780

O=C(O)C1=CC=COC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8901322 0.84
SCHEMBL4649117 0.83
SCHEMBL11414414 0.80
SCHEMBL3717741 0.78 TSHR (0.37)
SCHEMBL18770319 0.75
SCHEMBL6877297 0.72 TSHR (0.32)
SCHEMBL6877291 0.72 TSHR (0.32)
SCHEMBL36839 0.72
SCHEMBL7820213 0.71
Bromide SCHEMBL28859971 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113912418-B High-strength porous shale brick sintered by modified straw and preparation method thereof 安徽创新秸秆利用有限公司 2024-03-08 CN claimed
CN-106928046-B A kind of salicylic preparation method of 3,4,5,6- tetrafluoro 常州佳德医药科技有限公司 2019-10-18 CN claimed
CN-109966290-A Application and its pharmaceutical composition of the CID1067700 in the drug of preparation prevention and/or treatment cranial vascular disease 苏州大学 2019-07-05 CN claimed
CN-109415387-A Arginase inhibitor and its treatment use 昂科艾伦迪治疗法公司 2019-03-01 CN claimed
CN-105541774-B 3,4- dihydrocoumarin class compounds and its preparation method and application 华中师范大学 2018-06-15 CN claimed
CN-107176949-A A kind of preparation method of triazole pyrans hydrochloride 湖南华腾制药有限公司 2017-09-19 CN claimed
CN-106928046-A A kind of salicylic preparation method of 3,4,5,6 tetrafluoros 常州佳德医药科技有限公司 2017-07-07 CN claimed
EP-1536863-A1 USE OF CYCLOOXYGENASE-2 SELECTIVE INHIBITORS AND THROMBOLYTIC AGENTS FOR THE TREATMENT OR PREVENTION OF A VASO-OCCLUSIVE EVENT Pharmacia Corporation (US) 2005-06-08 EP claimed
WO-2004103300-A2 COMPOSITIONS AND METHODS OF TREATING REDUCED BLOOD FLOW TO THE CNS WITH COX-2 INHIBITORS AND CHOLINERGIC AGENTS PHARMACIA CORPORATION (US) 2004-12-02 WO claimed
WO-2004004833-A1 USE OF CYCLOOXYGENASE-2 SELECTIVE INHIBITORS AND THROMBOLYTIC AGENTS FOR THE TREATMENT OR PREVENTION OF A VASO-OCCLUSIVE EVENT PHARMACIA CORPORATION (US) 2004-01-15 WO claimed
CN-1365363-A thineopyranecarboxyamide derivatives RECORDATI CHEM PHARM (CH) 2002-08-21 CN claimed
EP-0977748-A1 SUBSTITUTED BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE &amp; CO. (US) 2000-02-09 EP claimed
WO-1998047890-A1 SUBSTITUTED BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1998-10-29 WO claimed
EP-4658640-A1 PYRIDIN-2(1H)-ONES AND PYRIMIDIN-4(3H)-ONES AS NLRP3 INHIBITORS Janssen Pharmaceutica NV (BE) 2025-12-10 EP disclosed
WO-2025137231-A1 METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS GILEAD SCIENCES, INC. (US) 2025-06-26 WO disclosed
EP-4568971-A1 ANTAGONISTS OF 5-HYDROXYTRYPTAMINE RECEPTOR SUBTYPE 2B Vanderbilt University (US) 2025-06-18 EP disclosed
WO-2001017516-A2 METHOD OF INHIBITING PROTEIN TYROSINE PHOSPHATASE 1B AND/OR T-CELL PROTEIN TYROSINE PHOSPHATASE AND/OR OTHER PTPASES WITH AN ASP RESIDUE AT POSITION 48 NOVO NORDISK A/S (DK) 2001-03-15 WO disclosed
CN-1257489-A Substituted benzopyran derivatives for the treatment of inflammation SEARLE & CO (US) 2000-06-21 CN disclosed
EP-0052912-B1 7-FLUORO-DIBENZO(B,F)THIEPIN DERIVATIVES, THEIR PREPARATION AND RESOLUTION, AND COMPOSITIONS CONTAINING THEM MERCK & CO. INC. (US) 1985-02-06 EP disclosed
EP-0052912-A1 7-Fluoro-dibenzo(b,f)thiepin derivatives, their preparation and resolution, and compositions containing them MERCK & CO. INC. (US) 1982-06-02 EP disclosed