Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1515253 | 0.83 | USP2 (0.57) | USP2SMN1; SMN2NR1H2RECQLHPGD | |
| SCHEMBL13979526 | 0.83 | RECQL (0.50) | USP2SMN1; SMN2RECQLHPGDEPHX1 | |
| SCHEMBL23890773 | 0.83 | USP2 (0.57) | USP2SMN1; SMN2NR1H2RECQLHPGD | |
| SCHEMBL16664672 | 0.83 | USP2 (0.57) | USP2SMN1; SMN2NR1H2RECQLHPGD | |
| SCHEMBL72535 | 0.81 | NR1H2 (0.51) | USP2SMN1; SMN2NR1H2RECQLHPGD | |
| SCHEMBL16893301 | 0.80 | NR1H2 (0.44) | USP2SMN1; SMN2NR1H2RECQLHPGD | |
| SCHEMBL17409638 | 0.80 | HPGD (0.50) | USP2SMN1; SMN2RECQLHPGDEPHX1 | |
| SCHEMBL3137077 | 0.78 | USP2 (0.41) | USP2SMN1; SMN2NR1H2RECQLHPGD | |
| SCHEMBL3126287 | 0.78 | USP2 (0.41) | USP2SMN1; SMN2NR1H2RECQLHPGD | |
| SCHEMBL16893292 | 0.78 | USP2 (0.41) | USP2SMN1; SMN2NR1H2RECQLHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838900-B1 | COMPOUNDS AND METHODS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES INC (US) | 2019-08-21 | — | — | EP | disclosed |