Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 13/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.68 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.56 |
| ▸ | FGFR4 | P22455 | 6/20 | 0.56 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15728605 | 0.95 | FGFR3 (0.70) | FGFR3KCNH2FGFR1FGFR4FGFR2 | |
| SCHEMBL18132723 | 0.90 | FGFR3 (0.66) | FGFR3KCNH2FGFR1FGFR4FGFR2 | |
| SCHEMBL15244414 | 0.89 | FGFR3 (0.62) | FGFR3KCNH2FGFR1FGFR4FGFR2 | |
| SCHEMBL15728561 | 0.89 | FGFR3 (0.84) | FGFR3KCNH2FGFR1FGFR4FGFR2 | |
| SCHEMBL15728641 | 0.86 | FGFR3 (0.75) | FGFR3KCNH2FGFR1FGFR4FGFR2 | |
| SCHEMBL15728439 | 0.86 | FGFR3 (0.73) | FGFR3KCNH2FGFR1FGFR4FGFR2 | |
| SCHEMBL15728610 | 0.85 | FGFR3 (0.69) | FGFR3KCNH2FGFR1FGFR4FGFR2 | |
| SCHEMBL15728485 | 0.84 | FGFR3 (0.65) | FGFR3KCNH2FGFR1FGFR4FGFR2 | |
| SCHEMBL15728559 | 0.84 | FGFR3 (0.71) | FGFR3KCNH2FGFR1FGFR4FGFR2 | |
| SCHEMBL15728643 | 0.84 | FGFR3 (0.71) | FGFR3KCNH2FGFR1FGFR4FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2821402-B1 | NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND | ASTELLAS PHARMA INC (JP) | 2019-08-21 | — | — | EP | disclosed |