SCHEMBL2128045

SCHEMBL2128045

CC(=O)N(CCCNCCCCN)C(C)=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 5/20 0.52
TDP1 Q9NUW8 1/20 0.48
CA12 O43570 2/20 0.48
F13A1 P00488 2/20 0.48
CA2 P00918 2/20 0.48
CYP1A2 P05177 2/20 0.48
ALOX15 P16050 2/20 0.48
CA4 P22748 2/20 0.48
CA6 P23280 2/20 0.48
CA5A P35218 2/20 0.48
THPO P40225 2/20 0.48
CA7 P43166 2/20 0.48
CA9 Q16790 2/20 0.48
CA14 Q9ULX7 2/20 0.48
CA5B Q9Y2D0 2/20 0.48
CA1 P00915 1/20 0.48
CA3 P07451 1/20 0.48
CYP2C9 P11712 1/20 0.48
PKM P14618 1/20 0.48
TSHR P16473 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1233715 0.96 PAOX (0.56) PAOXTDP1CA12F13A1CA2
SCHEMBL3143903 0.92 PAOX (0.56) PAOXTDP1CA12F13A1CA2
SCHEMBL27839874 0.88 PAOX (0.49) PAOXTDP1CA12F13A1CA2
SCHEMBL10448893 0.83 PAOX (0.46) PAOXCA12CA2CYP1A2ALOX15
SCHEMBL11793263 0.82 CYP2C9 (0.52) PAOXTDP1CA12CA2ALOX15
SCHEMBL1708094 0.81 PAOX (0.50) PAOXCA12CA2ALOX15CA4
SCHEMBL28003652 0.81 PAOX (0.50) PAOXCA12CA2ALOX15CA4
SCHEMBL9617304 0.81 PAOX (0.50) PAOXCA12CA2ALOX15CA4
SCHEMBL27860781 0.81 PAOX (0.42) PAOXCYP1A2ALOX15THPOTSHR
SCHEMBL22491057 0.80 CYP2C9 (0.50) PAOXTDP1CA12CA2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119968213-A Methods for detecting and treating ovarian cancer 德州大学系统董事会 2025-05-09 CN claimed
US-20250138016-A1 METHODS FOR THE DETECTION AND TREATMENT OF OVARIAN CANCER BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2025-05-01 US claimed
US-20240241107-A1 SERUM METABOLOMICS RELATED TO CHIMERIC ANTIGEN RECEPTOR (CAR) T-CELL THERAPY BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-07-18 US claimed
US-20240159753-A1 METHODS FOR THE DETECTION AND TREATMENT OF LUNG CANCER BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2024-05-16 US claimed
CN-117915926-A Serometabonomics associated with Chimeric Antigen Receptor (CAR) T cell therapy 得克萨斯州大学系统董事会 2024-04-19 CN claimed
WO-2024063545-A1 COMPOSITION COMPRISING LACTOBACILLUS PLANTARUM STRAIN FOR IMPROVING INTESTINAL METABOLITE COMPOSITION 주식회사 지아이바이옴 2024-03-28 WO claimed
EP-4333860-A1 SERUM METABOLOMICS RELATED TO CHIMERIC ANTIGEN RECEPTOR (CAR) T-CELL THERAPY Board of Regents, The University of Texas System (US) 2024-03-13 EP claimed
WO-2024020427-A2 METHODS FOR THE DETECTION AND TREATMENT OF OVARIAN CANCER BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-01-25 WO claimed
US-11851555-B2 Polybutene derivative for rubber compounding and rubber composition including same DL CHEMICAL CO., LTD. (KR) 2023-12-26 US claimed
EP-3943317-B1 POLYBUTENE DERIVATIVE FOR RUBBER COMPOUNDING AND RUBBER COMPOSITION INCLUDING SAME DL CHEMICAL CO LTD (KR) 2023-09-06 EP claimed
CN-116529603-A Methods for detecting and treating lung cancer 德州大学系统董事会 2023-08-01 CN claimed
WO-2022236131-A1 SERUM METABOLOMICS RELATED TO CHIMERIC ANTIGEN RECEPTOR (CAR) T-CELL THERAPY BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2022-11-10 WO claimed
US-20220025165-A1 POLYBUTENE DERIVATIVE FOR RUBBER COMPOUNDING AND RUBBER COMPOSITION INCLUDING SAME DL CHEMICAL CO., LTD. (KR) 2022-01-27 US claimed
EP-3943317-A1 POLYBUTENE DERIVATIVE FOR RUBBER COMPOUNDING AND RUBBER COMPOSITION INCLUDING SAME DC Chemical Co., Ltd. (KR) 2022-01-26 EP claimed
CN-113956378-A Polybutene derivative for rubber kneading and rubber composition containing the same DL化学株式会社 2022-01-21 CN claimed
US-9134313-B2 Method of detecting colorectal cancer of stages 0 to I TOKYO METROPOLITAN ORGANIZATION FOR MEDICAL RESEARCH (JP) 2015-09-15 US claimed
US-8404434-B2 Method for determining degree of negative effect of macrophages on vertebrate YAMASA CORPORATION (JP) 2013-03-26 US claimed
US-20100151585-A1 Method for determining degree of negative effect of macrophages on vertebrate HAMAOKI MASARU 2010-06-17 US claimed
US-7687231-B2 Method for determining degree of negative effect of macrophages on vertebrate YAMASA CORPORATION (JP) 2010-03-30 US claimed
US-20070202554-A1 Method for determining degree of negative effect of macrophages on vertebrate YAMASA CORPORATION (JP) 2007-08-30 US claimed