SCHEMBL21283017

SCHEMBL21283017

c1ccc(-c2ccc3oc4ccccc4c3c2)c(-c2ccc3oc4ccccc4c3c2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.57
KDM4E B2RXH2 3/20 0.57
ALDH1A1 P00352 3/20 0.57
HPGD P15428 3/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
NPC1 O15118 2/20 0.57
RAB9A P51151 1/20 0.57
AHR P35869 2/20 0.52
ALOX5 P09917 2/20 0.51
HSP90AA1 P07900 1/20 0.50
HSP90AB1 P08238 1/20 0.50
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C19 P33261 1/20 0.46
MAOA P21397 3/20 0.45
GLA P06280 1/20 0.45
CYP3A4 P08684 1/20 0.45
PGAM1 P18669 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15965728 0.98 MAPT (0.55) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL22250023 0.94 HPGD (0.52) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL16904369 0.94 MAPT (0.52) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL126539 0.93 MAPT (0.50) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL25052877 0.91 MAPT (0.49) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL27341813 0.89 MAPT (0.47) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL10478418 0.89 MAPT (0.63) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL2039941 0.89 MAPT (0.63) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL15835969 0.89 MAPT (0.63) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL15835950 0.89 MAPT (0.63) MAPTKDM4EALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11380850-B2 Organic electroluminescent devices comprising host compounds CYNORA GMBH (DE) 2022-07-05 US disclosed
EP-3535347-B1 ORGANIC ELECTROLUMINESCENT DEVICES COMPRISING HOST COMPOUNDS CYNORA GMBH (DE) 2021-03-03 EP disclosed
US-20190259958-A1 ORGANIC ELECTROLUMINESCENT DEVICES COMPRISING HOST COMPOUNDS SAMSUNG DISPLAY CO., LTD. (KR) 2019-08-22 US disclosed