Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 19/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 18/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2126786 | 0.92 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL983386 | 0.84 | HCRTR1 (0.43) | HCRTR1HCRTR2RORC | |
| SCHEMBL983384 | 0.84 | HCRTR1 (0.43) | HCRTR1HCRTR2RORC | |
| SCHEMBL982525 | 0.82 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL985097 | 0.82 | HCRTR1 (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL2127078 | 0.82 | HCRTR1 (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL2126913 | 0.82 | HCRTR1 (0.44) | HCRTR1HCRTR2 | |
| SCHEMBL983901 | 0.82 | HCRTR1 (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL2126072 | 0.82 | HCRTR1 (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL981787 | 0.81 | HCRTR1 (0.50) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247586-B1 | 2-AZA-BICYCLO[2.2.1]HEPTANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-04-25 | — | — | EP | disclosed |