SCHEMBL21284218

SCHEMBL21284218

Nc1ccn([C@@H]2O[C@@H]3COP(=O)(O)O[C@H]4C[C@H](n5cnc6c(N)ncnc65)O[C@@H]4COP(=O)(S)O[C@H]3[C@H]2F)c(=O)n1

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 20/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21307921 0.93 STING1 (0.73) STING1
SCHEMBL23800741 0.91 STING1 (0.78) STING1
SCHEMBL23800893 0.91 STING1 (0.78) STING1
SCHEMBL23798614 0.91 STING1 (0.78) STING1
SCHEMBL21284208 0.90 STING1 (0.72) STING1
SCHEMBL21283838 0.89 STING1 (0.69) STING1
SCHEMBL23895233 0.87 STING1 (0.67) STING1
SCHEMBL26201624 0.85 STING1 (0.87) STING1
SCHEMBL23798625 0.84 STING1 (0.89) STING1
SCHEMBL23476743 0.84 STING1 (0.89) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019161171-A1 NANOPARTICLE FORMULATIONS OF STING AGONISTS SPEROVIE BIOSCIENCES, INC. (US) 2019-08-22 — — WO disclosed
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