Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15064604 | 0.83 | BRD4 (0.38) | ALDH1A1LMNAKMT2APOLBL3MBTL1 | |
| SCHEMBL16447915 | 0.82 | BRD4 (0.37) | ALDH1A1LMNAKMT2APOLBL3MBTL1 | |
| SCHEMBL18567026 | 0.82 | HTT (0.35) | ALDH1A1LMNAKMT2ATDP1POLB | |
| SCHEMBL2415069 | 0.81 | KDM4E (0.38) | ALDH1A1LMNAKMT2ATDP1POLB | |
| SCHEMBL17967309 | 0.80 | PDE3B (0.33) | ALDH1A1LMNAKMT2APOLBPDE3B | |
| SCHEMBL18726317 | 0.79 | PDE3B (0.32) | PDE3BPDE3A | |
| SCHEMBL15084354 | 0.75 | BRD4 (0.36) | ALDH1A1LMNAKMT2APOLBL3MBTL1 | |
| SCHEMBL18726312 | 0.75 | GAA (0.38) | ALDH1A1KMT2APOLBL3MBTL1PDE3B | |
| SCHEMBL19755582 | 0.71 | BRD4 (0.37) | ALDH1A1LMNAKMT2APOLBL3MBTL1 | |
| SCHEMBL15084366 | 0.70 | HSD17B10 (0.40) | ALDH1A1LMNAKMT2ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019159199-A1 | CONTINUES FLOW PROCESS FOR THE PREPARATION OF ACTIVE PHARMACEUTICAL INGREDIENTS - POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVES AND INTERMEDIATES THEREOF | CIPLA LIMITED (IN) | 2019-08-22 | — | — | WO | disclosed |