Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | SORD | Q00796 | 5/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.31 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
| ▸ | PRKACA | P17612 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21268772 | 0.89 | F10 (0.39) | F10PARP1SORDDYRK1ADYRK1B | |
| SCHEMBL21274154 | 0.88 | F10 (0.38) | F10PARP1 | |
| SCHEMBL21273857 | 0.87 | F10 (0.37) | F10PARP1 | |
| SCHEMBL21268750 | 0.87 | F10 (0.39) | F10PARP1CDK9KMT2APOLB | |
| SCHEMBL21274174 | 0.87 | F10 (0.37) | F10PARP1SORDNPC1RAB9A | |
| SCHEMBL21274077 | 0.85 | F10 (0.36) | F10PARP1NPC1RAB9A | |
| SCHEMBL21268718 | 0.85 | F10 (0.36) | F10PARP1 | |
| SCHEMBL22822880 | 0.84 | F10 (0.36) | F10PARP1 | |
| SCHEMBL21274330 | 0.83 | F10 (0.35) | F10PARP1 | |
| SCHEMBL21274314 | 0.83 | F10 (0.35) | F10PARP1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019158731-A1 | PHARMACEUTICAL 6,5 HETEROBICYCLIC RING DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2019-08-22 | — | — | WO | disclosed |