Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 20/20 | 0.84 |
| ▸ | CD274 | Q9NZQ7 | 20/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21290581 | 0.92 | PDCD1 (1.00) | PDCD1CD274 | |
| SCHEMBL21290637 | 0.88 | PDCD1 (1.00) | PDCD1CD274 | |
| SCHEMBL21291114 | 0.87 | CD274 (1.00) | PDCD1CD274 | |
| SCHEMBL21290550 | 0.87 | CD274 (1.00) | PDCD1CD274 | |
| SCHEMBL21290544 | 0.86 | CD274 (1.00) | PDCD1CD274 | |
| SCHEMBL26329726 | 0.84 | PDCD1 (0.84) | PDCD1CD274 | |
| SCHEMBL21290996 | 0.84 | PDCD1 (1.00) | PDCD1CD274 | |
| SCHEMBL21290022 | 0.83 | PDCD1 (1.00) | PDCD1CD274 | |
| SCHEMBL21290900 | 0.83 | PDCD1 (1.00) | PDCD1CD274 | |
| SCHEMBL25610028 | 0.83 | PDCD1 (0.90) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019160882-A1 | PD-1/PD-L1 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2019-08-22 | — | — | WO | disclosed |