SCHEMBL21295963

SCHEMBL21295963

Cc1[c]cc2sccc2c1

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.37
DYRK1A Q13627 1/20 0.34
CA2 P00918 5/20 0.33
CA12 O43570 4/20 0.33
PTPRC P08575 1/20 0.31
PTPN6 P29350 1/20 0.31
PTPN11 Q06124 1/20 0.31
PTPN22 Q9Y2R2 1/20 0.31
HTR2C P28335 2/20 0.31
HTR2A P28223 1/20 0.31
CTNNB1 P35222 1/20 0.30
WNT3A P56704 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3812213 0.83 CYP2A6 (0.33) CYP2A6DYRK1AKDM4E
SCHEMBL980076 0.75 CYP2A6 (0.37) CYP2A6DYRK1APTPRCPTPN6PTPN11
SCHEMBL7976209 0.75 PDE10A (0.35) CYP2A6DYRK1ACA2CA12CTNNB1
SCHEMBL21295630 0.69 CTNNB1 (0.36) CYP2A6DYRK1ACA2CA12PTPRC
SCHEMBL164774 0.69 CYP2A6 (0.50) CYP2A6DYRK1ACA2CA12PTPRC
SCHEMBL826944 0.69 CYP2A6 (0.42) CYP2A6DYRK1ACA2CA12PTPRC
SCHEMBL21300585 0.67 DYRK1A (0.36) CYP2A6DYRK1ACTNNB1WNT3AKDM4E
SCHEMBL29698806 0.67 CYP2A6 (0.50) CYP2A6DYRK1ACA2CA12PTPRC
SCHEMBL155613 0.67 CYP2A6 (0.50) CYP2A6DYRK1ACA2CA12PTPRC
SCHEMBL1041559 0.66 CYP2A6 (0.48) CYP2A6DYRK1ACA2CA12PTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO disclosed
WO-2019163959-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCNET ELEMENT, AND ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2019-08-29 WO disclosed