Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 18/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21294888 | 1.00 | SCN9A (0.42) | SCN9AKDM1AMAOB | |
| SCHEMBL20063766 | 0.91 | SCN9A (0.48) | SCN9AKDM1AMAOB | |
| SCHEMBL20072906 | 0.91 | SCN9A (0.48) | SCN9AKDM1AMAOB | |
| SCHEMBL20063852 | 0.91 | SCN9A (0.48) | SCN9AKDM1AMAOB | |
| SCHEMBL20063765 | 0.91 | SCN9A (0.48) | SCN9AKDM1AMAOB | |
| SCHEMBL21306611 | 0.89 | SCN9A (0.53) | SCN9A | |
| SCHEMBL28487575 | 0.89 | SCN9A (0.53) | SCN9A | |
| SCHEMBL21306637 | 0.89 | SCN9A (0.50) | SCN9A | |
| SCHEMBL29482015 | 0.89 | SCN9A (0.50) | SCN9A | |
| SCHEMBL29482010 | 0.89 | SCN9A (0.50) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3759098-A1 | PYRIDINE-SULFONAMIDE COMPOUNDS AND THEIR USE AGAINST PAIN AND RELATED CONDITIONS | Genentech, Inc. (US) | 2021-01-06 | — | — | EP | disclosed |
| WO-2019165290-A1 | PYRIDINE-SULFONAMIDE COMPOUNDS AND THEIR USE AGAINST PAIN AND RELATED CONDITIONS | GENENTECH, INC. (US) | 2019-08-29 | — | — | WO | disclosed |