Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2129438 | 0.93 | NR1H4 (0.64) | NR1H4LIFR | |
| SCHEMBL2128873 | 0.91 | NR1H4 (0.64) | NR1H4LIFR | |
| SCHEMBL2128611 | 0.88 | NR1H4 (0.61) | NR1H4LIFR | |
| SCHEMBL2129752 | 0.84 | NR1H4 (0.65) | NR1H4LIFR | |
| SCHEMBL2127348 | 0.83 | NR1H4 (0.79) | NR1H4LIFR | |
| SCHEMBL2128452 | 0.82 | NR1H4 (0.62) | NR1H4LIFR | |
| SCHEMBL4427551 | 0.82 | NR1H4 (0.77) | NR1H4LIFR | |
| SCHEMBL2131102 | 0.81 | NR1H4 (0.67) | NR1H4LIFR | |
| SCHEMBL4426892 | 0.81 | NR1H4 (0.74) | NR1H4LIFR | |
| SCHEMBL2152268 | 0.81 | NR1H4 (0.77) | NR1H4LIFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2084147-B1 | HETEROCYCLIC FXR BINDING COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2012-04-25 | — | — | EP | disclosed |
| EP-2084147-A1 | HETEROCYCLIC FXR BINDING COMPOUNDS | Phenex Pharmaceuticals AG (DE) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008025540-A1 | HETEROCYCLIC FXR BINDING COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2008-03-06 | — | — | WO | disclosed |
| EP-1894924-A1 | Heterocyclic FXR binding compounds | Phenex Pharmaceuticals AG (DE) | 2008-03-05 | — | — | EP | disclosed |