Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 20/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21300767 | 0.76 | CTSC (0.46) | CTSCCTSK | |
| SCHEMBL22643048 | 0.75 | CTSC (0.60) | CTSC | |
| SCHEMBL21300790 | 0.75 | CTSC (0.46) | CTSC | |
| SCHEMBL12950177 | 0.75 | CTSC (0.44) | CTSCCTSK | |
| SCHEMBL22810844 | 0.73 | CTSC (0.44) | CTSC | |
| SCHEMBL19155199 | 0.72 | CTSC (0.46) | CTSCCTSK | |
| SCHEMBL13258901 | 0.71 | ACACB (0.41) | — | |
| SCHEMBL13072978 | 0.71 | ACACB (0.41) | — | |
| SCHEMBL16565966 | 0.68 | RECQL (0.46) | — | |
| SCHEMBL18084482 | 0.68 | CTSC (0.49) | CTSCCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3082877-B1 | CYTOTOXIC PEPTIDES AND CONJUGATES THEREOF | NOVARTIS AG (CH) | 2019-08-28 | — | — | EP | disclosed |