Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 17/20 | 0.82 |
| ▸ | PLG | P00747 | 2/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22883225 | 0.94 | FOLH1 (0.82) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL31635857 | 0.94 | FOLH1 (0.82) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL22883383 | 0.94 | FOLH1 (0.79) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL22883382 | 0.94 | FOLH1 (0.79) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL24374933 | 0.94 | FOLH1 (0.81) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL17706000 | 0.94 | FOLH1 (0.81) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL19296386 | 0.93 | FOLH1 (0.77) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL29679267 | 0.93 | FOLH1 (0.79) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL21310479 | 0.93 | FOLH1 (0.80) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL24334720 | 0.93 | FOLH1 (0.78) | FOLH1PLGPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019165200-A1 | CHEMICAL CONJUGATES OF EVANS BLUE DERIVATIVES AND THEIR USE AS RADIOTHERAPY AND IMAGING AGENTS FOR TARGETING PROSTATE CANCER | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2019-08-29 | — | — | WO | disclosed |