Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20096015 | 1.00 | HTR2C (0.51) | HTR2CDRD2HTR2AHTR2BLMNA | |
| SCHEMBL20096133 | 1.00 | HTR2C (0.51) | HTR2CDRD2HTR2AHTR2BLMNA | |
| SCHEMBL2532290 | 0.82 | HTR2C (0.72) | HTR2CDRD2HTR2AHTR2BKDM1A | |
| SCHEMBL20095724 | 0.80 | HTR2C (0.54) | HTR2CDRD2HTR2AHTR2BKDM1A | |
| SCHEMBL20095707 | 0.80 | HTR2C (0.54) | HTR2CDRD2HTR2AHTR2BKDM1A | |
| SCHEMBL20095686 | 0.80 | HTR2C (0.54) | HTR2CDRD2HTR2AHTR2BKDM1A | |
| SCHEMBL20095961 | 0.80 | HTR2C (0.54) | HTR2CDRD2HTR2AHTR2BKDM1A | |
| SCHEMBL20096265 | 0.80 | HTR2C (0.54) | HTR2CDRD2HTR2AHTR2BKDM1A | |
| SCHEMBL20095708 | 0.80 | HTR2C (0.54) | HTR2CDRD2HTR2AHTR2BKDM1A | |
| SCHEMBL23639074 | 0.79 | HTR2C (0.52) | HTR2CDRD2HTR2AHTR2BKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019165290-A1 | PYRIDINE-SULFONAMIDE COMPOUNDS AND THEIR USE AGAINST PAIN AND RELATED CONDITIONS | GENENTECH, INC. (US) | 2019-08-29 | — | — | WO | disclosed |