Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 20/20 | 0.74 |
| ▸ | GSK3B | P49841 | 19/20 | 0.74 |
| ▸ | CLK2 | P49760 | 3/20 | 0.67 |
| ▸ | CLK3 | P49761 | 3/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21292363 | 0.85 | DYRK1A (1.00) | DYRK1AGSK3BCLK2CLK3 | |
| SCHEMBL21292248 | 0.85 | DYRK1A (1.00) | DYRK1AGSK3BCLK2CLK3 | |
| SCHEMBL21292243 | 0.81 | DYRK1A (1.00) | DYRK1AGSK3BCLK2CLK3 | |
| SCHEMBL21292387 | 0.80 | DYRK1A (1.00) | DYRK1AGSK3BCLK2CLK3 | |
| SCHEMBL21292299 | 0.80 | DYRK1A (1.00) | DYRK1AGSK3BCLK2CLK3 | |
| SCHEMBL21292275 | 0.79 | GSK3B (1.00) | DYRK1AGSK3BCLK2CLK3 | |
| SCHEMBL21292308 | 0.79 | DYRK1A (1.00) | DYRK1AGSK3BCLK2CLK3 | |
| SCHEMBL21292319 | 0.78 | DYRK1A (1.00) | DYRK1AGSK3BCLK2CLK3 | |
| Hydrochloric Acid SCHEMBL23533920 | 0.77 | DYRK1A (0.81) | DYRK1AGSK3BCLK2CLK3 | |
| SCHEMBL21292294 | 0.77 | DYRK1A (1.00) | DYRK1AGSK3BCLK2CLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019165192-A1 | 5-HETEROARYL SUBSTITUTED INDAZOLE-3-CARBOXAMIDES AND PREPARATION AND USE THEREOF | SAMUMED, LLC (US) | 2019-08-29 | — | — | WO | disclosed |