Glucuronate

Glucuronate

SCHEMBL21312643

O=C(O)C1OC(O)[C@H](O)C(O)[C@@H]1O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
IDUA P35475 1/20 0.50
SUCNR1 Q9BXA5 1/20 0.48
FGF2 P09038 1/20 0.37
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 2/20 0.36
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
AKT1 P31749 1/20 0.33
HIF1A Q16665 1/20 0.31
AHCY P23526 1/20 0.31
TMEM97 Q5BJF2 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
GLA P06280 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
HSD17B10 Q99714 1/20 0.31
GBA1 P04062 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glucuronate SCHEMBL13324585 1.00 IDUA (0.50) IDUASUCNR1FGF2KDM4EALDH1A1
Glucuronate SCHEMBL15596891 1.00 IDUA (0.50) IDUASUCNR1FGF2KDM4EALDH1A1
Glucuronate SCHEMBL15177391 1.00 IDUA (0.50) IDUASUCNR1FGF2KDM4EALDH1A1
Glucuronate SCHEMBL20094857 1.00 IDUA (0.50) IDUASUCNR1FGF2KDM4EALDH1A1
Glucuronate SCHEMBL13376995 1.00 IDUA (0.50) IDUASUCNR1FGF2KDM4EALDH1A1
Glucuronate SCHEMBL6404275 1.00 IDUA (0.50) IDUASUCNR1FGF2KDM4EALDH1A1
Glucuronate SCHEMBL25253417 1.00 IDUA (0.50) IDUASUCNR1FGF2KDM4EALDH1A1
Glucuronate SCHEMBL21792734 1.00 IDUA (0.50) IDUASUCNR1FGF2KDM4EALDH1A1
Glucuronate SCHEMBL22749019 1.00 IDUA (0.50) IDUASUCNR1FGF2KDM4EALDH1A1
Glucuronate SCHEMBL6514487 1.00 IDUA (0.50) IDUASUCNR1FGF2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210403903-A1 MICROBEADS FOR TAGLESS ENCODED CHEMICAL LIBRARY SCREENING Nanna Therapeutics Limited (GB) 2021-12-30 US disclosed
US-20190264199-A1 TAGLESS ENCODED CHEMICAL LIBRARY Nanna Therapeutics Limited (GB) 2019-08-29 US disclosed