Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.45 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16344674 | 0.87 | PTGDR2 (0.45) | PTGDR2PPARGKDM4EMEN1ALDH1A1 | |
| SCHEMBL16344949 | 0.74 | PTGDR2 (0.46) | PTGDR2PPARGKDM4EMEN1ALDH1A1 | |
| SCHEMBL18378565 | 0.74 | PTGDR2 (0.46) | PTGDR2PPARGKDM4EMEN1ALDH1A1 | |
| SCHEMBL18378354 | 0.73 | PTGDR2 (0.45) | PTGDR2PPARG | |
| SCHEMBL15176400 | 0.72 | PTGDR2 (0.40) | PTGDR2KDM4E | |
| SCHEMBL16344621 | 0.72 | PTGDR2 (0.44) | PTGDR2PPARGKDM4EMEN1ALDH1A1 | |
| SCHEMBL24380768 | 0.72 | PTGER4 (0.42) | PTGDR2 | |
| SCHEMBL24380803 | 0.71 | EZH2 (0.43) | PTGDR2 | |
| SCHEMBL15175836 | 0.71 | PTGDR2 (0.57) | PTGDR2KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL16344944 | 0.71 | PTGDR2 (0.57) | PTGDR2KDM4EMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2875012-B1 | 5HT3 RECEPTOR ANTAGONISTS | TAKEDA PHARMACEUTICALS CO (JP) | 2019-09-04 | — | — | EP | disclosed |