Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530892 | 0.78 | TSHR (0.34) | MAPTALDH1A1GAALMNAKDM4E | |
| SCHEMBL9530887 | 0.78 | TSHR (0.34) | MAPTALDH1A1GAALMNAKDM4E | |
| SCHEMBL19390292 | 0.76 | MAPT (0.43) | MAPTALDH1A1GAALMNAKDM4E | |
| SCHEMBL19538786 | 0.73 | MAPT (0.45) | MAPTALDH1A1GAALMNAKDM4E | |
| SCHEMBL3735404 | 0.73 | CYP2C9 (0.61) | MAPTALDH1A1GAALMNAKDM4E | |
| SCHEMBL29558213 | 0.73 | CYP2C9 (0.61) | MAPTALDH1A1GAALMNAKDM4E | |
| SCHEMBL19390276 | 0.73 | MAPT (0.41) | MAPTALDH1A1GAALMNAKDM4E | |
| SCHEMBL3735405 | 0.73 | CYP2C9 (0.61) | MAPTALDH1A1GAALMNAKDM4E | |
| SCHEMBL13257963 | 0.72 | NPC1 (0.54) | MAPTALDH1A1GAALMNAKDM4E | |
| SCHEMBL3127028 | 0.70 | MAPT (0.50) | MAPTALDH1A1GAALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3252045-B1 | CYANOGUANIDINES AND THEIR USE AS ANTIVIRAL AGENTS | ABBVIE INC (US) | 2019-09-04 | — | — | EP | disclosed |