Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.61 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL28477001 | 0.81 | TLR7 (0.65) | TLR7NUDT1 | |
| SCHEMBL21318954 | 0.79 | TLR7 (0.65) | TLR7NUDT1 | |
| SCHEMBL18207513 | 0.78 | TLR7 (0.55) | TLR7NUDT1 | |
| SCHEMBL18207749 | 0.78 | TLR7 (0.56) | TLR7 | |
| SCHEMBL21318931 | 0.77 | TLR7 (0.65) | TLR7NUDT1 | |
| SCHEMBL18221022 | 0.77 | TLR7 (0.75) | TLR7 | |
| SCHEMBL3133950 | 0.77 | TLR7 (0.77) | TLR7NUDT1 | |
| SCHEMBL16206181 | 0.77 | TLR7 (1.00) | TLR7NUDT1 | |
| SCHEMBL18207523 | 0.77 | TLR7 (0.53) | TLR7NUDT1 | |
| SCHEMBL18207419 | 0.76 | TLR7 (0.58) | TLR7NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3294740-B1 | NOVEL SULFONIMIDOYLPURINONE COMPOUNDS AND DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF VIRUS INFECTION | HOFFMANN LA ROCHE (CH) | 2019-09-04 | — | — | EP | disclosed |